When nutrients are food-based instead of synthetic, they are typically easier for the body to absorb and use because in nature, vitamins and minerals come packaged with other beneficial compounds like fiber, enzymes, and antioxidants. These natural cofactors help enhance the nutrient's bioavailability, meaning the body can recognize and utilize them more efficiently than isolated, lab-created synthetic versions. Food-based nutrients are found in whole foods, whereas synthetic nutrients are manufactured in a lab through chemical processes.